Update:
#insert Lyx note is also quite helpful
#⌥⌘n
\bind "C-A-n" "note-insert"
Here are my top 3 keyboard shortcuts that are missing in LyX's standard settings:
#insert reference (de: "Einfügen -> Querverweis")
#⌥⌘R
\bind "C-A-r" "dialog-show-new-inset ref"
#insert label (de: "Einfügen -> Marker")
#⌥⌘M
\bind "C-A-m" "label-insert"
#citation (de: "Einfügen -> Literaturverweis")
#⌥⌘Z
\bind "C-A-z" "citation-insert"
Being on a Mac, place them as user.bind in ~/Library/Application Support/LyX-2.0/bind/
Restart LyX and off you go, saving yourself them awkward mouse-clicks.